Pepcid

Histamine is a chemical made by the body that stimulates cells lining the stomach to produce acid. Pepcid belongs to a class of medications called H2-blockers that blocks the action of histamine on stomach cells, thus reducing production of acid by the stomach. Other H2 blockers include cimetidine (Tagamet), ranitidine (Zantac), and nizatidine (Axid). Pepcid was approved by the FDA in November, 1986.

Pepcid blocks the action of histamine on stomach cells, and reduces stomach acid production. Pepcid is useful in promoting the healing of stomach and duodenal ulcers and in reducing ulcer pain. Pepcid has been effective in preventing recurrence of ulcers when given in low doses for prolonged periods of time. Pepcid also is used for treating heartburn and in healing ulceration and inflammation of the esophagus (esophagitis) resulting from acid (gastroesophageal reflux disease or GERD). High doses are used for treating conditions in which there are marked increases in acid secretion such as Zollinger-Ellison syndrome.