Phenergan

Phenergan is a phenothiazine in the same class of drugs as chlorpromazine (Thorazine) and trifluoperazine (Stelazine); however, unlike the other drugs in this class, Phenergan is not used clinically as an anti-psychotic. It acts as an anti-histamine, a sedative, and an anti-emetic (anti-nausea). Phenergan is used principally as an anti-emetic, to prevent motion sickness or as an anti-histamine in combination with other medications in cough and cold preparations. Phenergan was approved by the FDA in 1951.

Phenergan is used to prevent motion sickness, nausea or vomiting, itching associated with allergies or for sedation.